Discover the possibilities on this approximately 0.43-acre parcel in Lake City, offering about 148 feet of road frontage and convenient access from a paved road. The property is currently zoned CN-Commercial Neighborhood-providing potential for neighborhood-oriented businesses designed to serve the surrounding community. Possible uses may include select retail shops, professional or business offices, personal-service businesses, barber or beauty shops, pharmacies, hardware stores, food-related retail, and other compatible commercial services, subject to Columbia County approval, development standards, utilities, parking requirements, and permitting. Positioned near US-90 with convenient access to I-75, the property offers visibility and connectivity for customers, employees, and deliveries. Downtown Lake City, shopping, restaurants, medical services, schools, and everyday conveniences are all within easy reach. Lake City serves as an important North Florida crossroads, connecting the region through I-75, I-10, US-90, and US-441. Gainesville is approximately an hour away, while Jacksonville, Tallahassee, and Valdosta are accessible for regional business, travel, healthcare, and entertainment. Lake City is known for its welcoming small-town atmosphere, growing commercial base, and proximity to some of North Florida's most appealing outdoor destinations. Residents and visitors enjoy nearby freshwater springs, rivers, state parks, trails, fishing, paddling, and recreation, including Ichetucknee Springs, O'Leno State Park, Osceola National Forest, and the Suwannee River region. With commercial zoning, substantial road frontage, and convenient access to major transportation routes, this parcel presents an appealing opportunity for an owner-user, local entrepreneur, developer, or investor looking for strategically located land in Columbia County. The property's Future Land Use designation is Residential-Low, so buyers should confirm their proposed use, building requirements, utility availability, and development plans directly with Columbia County Planning and Zoning before purchasing.